Botox 50 Units | Botulinum Toxin A

Botox 50 Units Injection Vial Contains botulinum toxin type A used to block acetylcholine release in the treatment of chronic sialorrhea, muscle spasticity, and dystonia, as well as in cosmetic applications.

What is Use of Botox 50 Units Injection Vial?

Botox 50IU toxin A is used for a variety of conditions, depending on the preparations. 

Cosmetically, Botox 50 Units Injection is used for the treatment of facial fine lines and wrinkles, specifically for upper facial rhytides, including forehead, lateral canthus, and glabellar lines.

In addition to the above Botox 50 Units Vial Injection is used for the following conditions: 

• Adults with symptomatic overactive bladder with or without incontinence
• Incontinence in adult patients who are not candidates for anticholinergic therapy
• Neurogenic Detrusor Overactivity (NDO) in patients over 5 years who cannot undergo anticholinergic therapy. 

Botulinum toxin A Allergan Botox Injection is used for the prevention of chronic migraines and for the treatment of muscle spasms, cervical dystonia, axillary hyperhidrosis, strabismus, and disorders of the 7th cranial nerve.

Off-label Use of Botox 50IU Injection:

Botox 50 Units (Botulinum toxin A) is used for a variety of conditions such as: 

• Temporomandibular joint (TMJ) disorders and myofascial pain
• Neurogenic thoracic outlet syndrome
• Epicondylitis
• Post-stroke pain
• Post-herpetic neuralgia
• Diabetic neuropathy
• Trigeminal neuralgia
• Neuropathic pain
• Spinal cord injury
• Bladder pain

How Botox 50 Units Injection Works?

Botox 50 injection blocks the release of acetylcholine, relieving muscle contractions, and is associated with a number of conditions, such as incontinence and dystonia.

Cosmetically, botulinum toxin A temporarily paralyzes facial muscles to treat wrinkles. The maximum effect of muscle paralysis occurs four to seven days after a single dose. When injected in therapeutic doses, botulinum toxin A causes partial chemical inhibition of muscle tissue.

• Causes a local decrease in muscle activity
• Muscle atrophy can result
• Axonal sprouting can begin
• Extra junctional acetylcholine receptors may form
• Botulinum toxin A can cause muscle repolarization, reversing muscle denervation

Mechanism of action

Botox 50 Units toxin type A blocks neuromuscular transmission at sympathetic nerve terminals, inhibiting the release of acetylcholine.

Allergan Botox Injection Botulinum toxins have actions at various regions: The neuromuscular junction, the autonomic ganglia, and both postganglionic sympathetic and parasympathetic nerve endings.

The heavy chain of the toxin binds selectively to the presynaptic surface of cholinergic neurons in an irreversible fashion. After binding, the toxin-receptor complex is taken into the cell by endocytosis.

The disulfide bond between the two chains is broken and the botulism toxin enters the cytoplasm. The light chain specifically interacts with SNAP-25 in nerve terminals to block the binding of acetylcholine vesicles to the cell membrane. SNAP-25 is essential for the successful binding and release of acetylcholine from vesicles in nerve endings.

Storage:

Store Botox 50 Units Injection in a refrigerator between 2-8°C.